Scientists in Atlantic Canada have found a gene that may play a role in skin aging. They were investigating the genetic cause of a rare disorder: the cutis laxa type 2 ( CL2), which causes skin on the hands, feet and face to be loose and older looking, when they discovered correlations with the synthesis of proline.
Several Maritime Canadian families with CL2 were identified and scientists were able to identify the gene responsible for CL2 in these patients, citing an interruption of the metabolism of the amino acid.
The findings are published in the current online issue of American journal of human genetics and are part of the Atlantic Medical Genetic and Genomic Initiative (AMGGI).
Biotechnology focus, August 2009, p9.
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